Diphtheria (Corynebacterium diphtheriae)

Corynebacteria are Gram-positive, aerobic, nonmotile, rod-shaped bacteria related to the Actinomycetes. They do non form spores or dissever as do the actinomycetes, merely they ware the characteristic of forming second base shaped, club-shaped or V-shaped arrangements in conventionality growth. They endure snapping movements just after(prenominal) cell division which brings them into characteristic arrangements resembling Chinese letters. The genus Corynebacteria consists of a respective(a) group of bacteria including wight and plant pathogens, as well as saprophytes. Some corynebacteria are give away of the normal flora of creation, finding a suitable niche in virtually every anatomical reference site. The best known and most astray canvas species is Corynebacterium diphtheriae, the causal agentive role of the illness diphtheria. History and Background No bacterial disease of humans has been as success plenteousy canvas as diphtheria. The etiology, mode of transmission, infectious mechanism and molecular terra firma of exotoxin structure, function, and reach have been clearly established. Consequently, highly effective methods of preaching and prevention of diphtheria have been developed. The theater of operations of Corynebacterium diphtheriae traces closely the development of medical microbiology, immunology and molecular biology. Many contributions to these fields, as well as to our understand of host-bacterial interactions, have been made studying diphtheria and the diphtheria toxin. Hippocrates provided the archetypical clinical description of diphtheria in the quaternary century B.C.

There are besides references to the disease in superannuated Syria and Egypt. In the 17th century, murderous epidemics of diphtheria move Europe; in Spain El garatillo (the strangler), in Italy and Sicily, the gullet disease. In the 18th century, the disease reached the American colonies and reached epidemic proportions in 1735. Often, square families died of the disease in a few weeks. The bacterium that caused diphtheria was first described by Klebs in 1883, and was cultivated by Loeffler in 1884, who employ Kochs postulates and properly identified Corynebacterium... If you want to maintain a full essay, rescript it on our website: Ordercustompaper.com

If you want to get a full essay, wisit our page: write my paper