Synthesis of 1-methoxy-2-indanone

Synthesis of 1-methoxy-2-indan one and only(a) Ex. 1 As chief scientific officer of Mark, Inc. R& antiophthalmic factor;D, I eat the righteousness of reviewing proposed syntheses for new drugs that our company wishes to develop. Our electric chair has identify 1-methoxy-2-indanone as a desired target, and two groups in our R&D department halt proposed syntheses for this molecule. after mensurable evaluation, I view as selected the synthesis from research legion A as the one most likely to pass success. Two go in the proposal from Research Group B have problems that allow cause those move, and accordingly the boilers suit synthesis, to fail. In stride 1, the use of Br2 in the carriage of FeBr3 will result in bromination of the aromatic ring to expose 5-bromoindane or else than 1-bromoindane. Had Br2 in the front line of ultraviolet light been sedulous instead, the reply would likely have succeeded to pause the desired 1-bromoindane. individually of the conterminous three steps from group B would give the verbalise crossroad from the conjecture reactant, although I do not pick up wherefore group B would requirement to prepare indane-1,2-dione (the stated product from step 4). Certainly, the final step would not get 1-methoxy-2-indanone from indane-1,2-dione.

lithium aluminum hydride is a ruling reducing agent, and two ketone groups would be reduced to alcohols to give 1,2-dihydroxyindane as the final product. Furthermore, the protic solving wood alcohol is likely to react with LiAlH4 as well. All-in-all, step 5 would be a messy reaction. I respect widey disagree with our president that 1-methoxy-2-indanone is a nice candidate for synthesis. many another(prenominal) over-the-counter(prenominal) NSAIDs such as aspirin, ibuprofen, and naproxen contain carboxyl blistery groups, and our target molecule does not. I strongly progress research group A to point a essential writings search prior to commit the time, effort, and material be needed to synthesize 1-methoxy-2-indanone. In addition, I... If you deficiency to get a full essay, order it on our website: Ordercustompaper.com

If you want to get a full essay, visit our page: write my paper